Is the product monoclonal or polyclonal?
There are three products in this range:
Z350 Polyspecific AHG - this is a blend of monoclonal anti-C3 (cell line 3G8, IgG) and rabbit polyclonal anti-IgG
Z356 Monospecific Anti-IgG - this is a rabbit polyclonal anti-IgG
Z360 Anti-Human C3 (Monoclonal) - this is monoclonal anti-C3 (cell line 3G8, IgG)
Are the products CE Marked?
All products in this range are CE Marked.
Are the products ready for use?
All products are supplied ready for use.
What controls should I use?
This is detailed on the IFU for each product. Every batch of antiglobulin tests should include a suitable positive (sensitivity) control, eg R1r cells sensitised with a weak anti-Rh(D). A method to prepare red blood cells sensitised with complement is published in the Guidelines for the Blood Transfusion Services in the United Kingdom.
What tests can I use these products for?
The products can be used for both Direct Antiglobulin Tests (DAT) and Indirect Antiglobulin Tests (IAT), sometimes referred to as the Coombs test. The products can be used in both NIS and LIS tests.
Why is the AHG product green in colour?
The AHG reagent is a green colour in accordance with guidelines and as a method to confirm the addition of the reagent to the test.
Does the product detect C3b or C3d?
Products Z350 and Z360 contain an antibody derived from cell line 3G8 which is specific to the C3d component of complement. These products will bind to cell bound complement components C3b and C3d.
Are these products available in bulk?
All products in this range can be supplied as bulk finished or for further manufacturing use (FFMU). For further information please contact firstname.lastname@example.org
What other products might I need?
Alba Bioscience also supply IgG Sensitised Cells (Product Code Z441) which can be used in the confirmation and control of antiglobulin tests. We also supply a full range of control products, including Anti-D 0.3iu/mL (Product Code Z251) for use in the control of antiglobulin tests.
Anti-IgG 1 and anti-IgG3 monoclonal material is also available from Alba Bioscience.